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Obese Patients Risk Misdiagnosis

. Friday, September 16, 2011
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Main Category: Obesity / Weight Loss / Fitness
Also Included In: Respiratory / Asthma
Article Date: 20 Aug 2011 - 0:00 PDT window.fbAsyncInit = function() { FB.init({ appId: 'aa16a4bf93f23f07eb33109d5f1134d3', status: true, cookie: true, xfbml: true, channelUrl: 'http://www.medicalnewstoday.com/scripts/facebooklike.html'}); }; (function() { var e = document.createElement('script'); e.async = true; e.src = document.location.protocol + '//connect.facebook.net/en_US/all.js'; document.getElementById('fb-root').appendChild(e); }()); email icon email to a friend   printer icon printer friendly   write icon opinions  
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The prevalence of physician-diagnosed asthma is increasing partly because of a link between asthma and obesity.

Several factors lead to asthma-like symptoms in obese patients, including the mechanical effect of increased body mass index on lung volumes, which increases the work required for breathing.

Researchers from the Countess of Chester Hospital and the University of Liverpool in the United Kingdom recently found that obese patients may be more at risk for asthma misdiagnosis due to the similarity of symptoms experienced, such as breathlessness. Out of 91 subjects, 33 (36.3%) experienced a possible misclassification of an asthma diagnosis.

This article is published in the July issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians: CHEST. doi:10.1378/chest.11-0948.

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Man Drops From 350 To 175 Lbs Because He Was Scared Of Diagnosis

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Editor's Choice
Main Category: Obesity / Weight Loss / Fitness
Also Included In: Nutrition / Diet;  Sports Medicine / Fitness;  Diabetes
Article Date: 29 Jul 2011 - 13:00 PDT window.fbAsyncInit = function() { FB.init({ appId: 'aa16a4bf93f23f07eb33109d5f1134d3', status: true, cookie: true, xfbml: true, channelUrl: 'http://www.medicalnewstoday.com/scripts/facebooklike.html'}); }; (function() { var e = document.createElement('script'); e.async = true; e.src = document.location.protocol + '//connect.facebook.net/en_US/all.js'; document.getElementById('fb-root').appendChild(e); }()); email icon email to a friend   printer icon printer friendly   write icon opinions  
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Will Nevin, 25, feared a frightening diagnosis by doctors so much that he went on a diet and exercise drive and lost 175 lbs in 11 months. He had been starting to have tingling sensations in his feet, which after an internet search made him wonder whether he might be pre-diabetic.

One day, in January 2010, while travelling with friends by car from Alabama to California, he felt a tightening in the chest and a racing heart. He assumed the worst and thought that perhaps he was having a heart attack. He kept quiet about his symptoms, saying nothing to his friends. Now, he realizes that was probably not a very wise thing to do.

The symptoms slowly went away and the road trip continued. He had not seen a doctor for three years. A fear lingered in the back of his mind that there might be something seriously wrong with his health. This fear grew and eventually pushed him into doing something about it.

Back in Alabama he continued wondering whether he had some serious and perhaps life-threatening condition. The worry sometimes overwhelmed him, but he kept it to himself. Today, on reflection, he says he was "wallowing in self pity."

A month passed, the worries continued, but so did his lifestyle of eating and watching TV - a lifestyle of physical inaction and eating. And then, suddenly, for no clear reason that he can recall, he walked to his university gym.

During his walk he acknowledged to himself that at the age of 24 a human is usually at the peak of his/her physical condition. If he was unfit, unhealthy, and flabby and weak at that age, then that peak either passed a long time ago or would never occur, he thought.

He remembers that his first trip into the gym was like going into a strange and unfamiliar land, except of course, for the smoothie counter. He got onto a treadmill and managed to do a three-mile walk on it.

From that day on he did not miss one day at the gym. He also carried out some research and altered his eating habits, cutting down on red meat meals and increasing his intake of veggies and fruits.

He did not see a doctor, nutritionist, gym instructor or sports scientist for advice - something he says today he regrets. He believes he was lucky that everything turned out well.

There were moments in the gym when he would look around and see nothing but perfect bodies, and would feel despondent and lonely. Negative thoughts of never ever being able to look like them occasionally entered his mind.

He found himself becoming frustrated and upset when he weighed himself and was disappointed with the results. This is a common problem - individuals with high expectations becoming frustrated and upset on the scale.

However, he persevered and people and family started to notice. Such comments as "You look different.." gradually turned into "Wow! I cannot recognize you any more..". Clothes starting becoming unwearable and he had to get new ones.

Nevin, who was studying law, felt a great sense of achievement when he managed to walk up the flight of stairs to his law class without panting. Today he says he can sprint up them with ease.

After 11 months Nevin weighed in at 175 pounds, a 50% drop in bodyweight. He had arrived, after many months, at that magic number - 175!

Even today he says he looks at himself in the mirror and still cannot believe it is him.

Now he was ready to see his doctor for a check-up, he thought. Whatever he was told he felt he could cope with. He passed with flying colors - he was fine, a healthy young man.

Prediabetes - this is when an individual's blood sugar level is abnormally high, but not enough for a diagnosis of diabetes type two to be made. The person is nearly at the threshold, knocking on the diabetes door. If nothing is done, such as losing weight, changing diet, and doing more exercise, most likely the person will eventually develop diabetes. Even at the pre-diabetes stage, damage to some organs, such as the heart, may already be starting to happen.

People need to know that the progression from pre-diabetes to diabetes type 2 is not inevitable, it is preventable. In most cases, all you have to do is more exercise, lose weight, and eat healthy foods.

Obesity in the USA - obesity rates have been increasing progressively in America for the last thirty years. In most other industrialized nations, and many other countries rates have also been rising. However, the USA rates are among the highest in the world. In 1997 it was estimated that 19.4% of adults were obese, this rose to 24.5% in 2004, 26.6% in 2007, to 33.8% in 2008 (Source: CDC).

Written by Christian Nordqvist
Copyright: Medical News Today
Not to be reproduced without permission of Medical News Today

Article Reference:
CNN, Wikipedia, BBC, CDC.Bookmark and Share

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posted by Qwerty on 29 Jul 2011 at 1:55 pm

Did he ever find his a1c level?

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posted by Heather on 29 Jul 2011 at 1:59 pm

Taking responsibility for his own health! Many can learn from him. Health does not come in a bottle, box, or pill. Way to go :)

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posted by Peg on 29 Jul 2011 at 2:15 pm

WOW! I am so impressed with this young man's determination and willingness to do what he needed to in order to get himself healthy! Way to go!

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posted by Myka on 29 Jul 2011 at 2:18 pm

While he should have done this with the guidance of a professional, I applaud that he did it in a healthy manner without resorting to extreme crash/fad dieting. The focus on weight loss should be more about health and less about looks. When the former is achieved, the latter will be close behind.
It's easy to get discouraged when one is not getting the desired effects right away, but an effective, long-term wieght loss plan takes time. It's very important to keep that in mind.

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posted by Liz on 29 Jul 2011 at 2:18 pm

This story must be spread throughout the country to indivdiuals realize how easily preventable obesity, and all the diseases along with it are. The statistics with mortality rates are pathetic.

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posted by Elaine Connelly on 29 Jul 2011 at 2:34 pm

I am not obese, I exercise moderately, try to eat fruits, vegetables, try to not eat much red meat. My entire Maternal side of the family all ended up with diabetes 2. I am on meds, take them faithfully. Try to monitor my blood sugar. And I still cannot get any lower than I currently am. Sometimes you get handed a genetic disposition which proves to be insurmountable.

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posted by Johan on 31 Jul 2011 at 10:23 am

Elaine Connelly wrote: "try to eat fruits, vegetables, try to not eat much red meat".
Well perhaps we should send someone over to threaten you with a gun and you won't TRY anymore. YOU WILL eat it!
Everyone who's ever improved their health (I've even been slim my entire life) knows its always possible to eat a little better. Even if you look like a super-model. And I say "eat better" not "eat less" because that is not a solution.
So stop eating those carbs and perhaps you will see results even sooner than you think.

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posted by Uzomah on 1 Aug 2011 at 1:22 am

I am highly encouraged by the work that this young man took. I need to so the same. Thanks for woting the article. I would prefer not to be scare to an ideal weight, but I have not done it yet. Maybe, should just do as an earlier post read" do not try, just doi it". thanks, I am encouraged. I plan to do what I need to do to achieve better health.

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Average Brit Spends £58,201 ($93,000) On Booze Over A Lifetime And Has 726 Hangovers

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These figures were reported today by Benenden Healthcare.

"Day by day, we may not notice our drinking habits and may not think about what it's costing us. But add it all up and the amounts become quite staggering.

Recommended guidelines for alcohol consumption are 3-4 units per day in men, equating to around a pint and a half of 4% strength beer, and 2-3 units in women - a single 175 ml glass of 13% strength wine for women. This means that by getting through 456 drinks a year on average, many Brits are sailing perilously close to the wind and, in many cases, most likely exceeding guidelines.

The yearly financial cost of this level of consumption also gives pause for thought, with £962 a year being no small sum for many families in the UK.

Benenden Healthcare wishes to draw attention to these levels of alcohol consumption, which not only pose a medical risk but a lifestyle risk in terms of financial cost. With 726 hangovers and being £58,201 out-of-pocket, 'enjoying a drink' regularly takes on a new dimension."

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Restaurant Calorie Counts Can Miss the Mark: Study

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Hysterectomy In Germany

. Thursday, September 15, 2011
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Main Category: Women's Health / Gynecology
Also Included In: Cosmetic Medicine / Plastic Surgery;  Stroke;  Heart Disease
Article Date: 12 Aug 2011 - 1:00 PDT window.fbAsyncInit = function() { FB.init({ appId: 'aa16a4bf93f23f07eb33109d5f1134d3', status: true, cookie: true, xfbml: true, channelUrl: 'http://www.medicalnewstoday.com/scripts/facebooklike.html'}); }; (function() { var e = document.createElement('script'); e.async = true; e.src = document.location.protocol + '//connect.facebook.net/en_US/all.js'; document.getElementById('fb-root').appendChild(e); }()); email icon email to a friend   printer icon printer friendly   write icon opinions  
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Hysterectomy elevates the risk of stroke and coronary heart disease in young women when combined with the removal of both ovaries in the same operation. This fact provides the background for the epidemiological report by Andreas Stang and colleagues on hysterectomy rates in Germany, which appears in the current issue of Deutsches Arzteblatt International (Dtsch Arztebl Int 2011; 108[30]: 508 - 14).

Removal of the uterus (hysterectomy) is among the commonest procedures in surgical gynecology. Stang et al. based their report on nationwide statistics relating to diagnosis-related groups (DRGs) in Germany for the years 2005 and 2006. They found that 4% of women under 50 who underwent hysterectomy for an indication other than cancer had a bilateral oophorectomy in the same operation, even though recent studies have shown that this is associated with an elevated risk of stroke and coronary heart disease.

The epidemiologists' assessment also revealed marked regional variation in hysterectomy rates across Germany. Fewer women underwent hysterectomy for benign indications in Hamburg, for example, than in Mecklenburg-West Pomerania over the same interval. Factors influencing the hysterectomy rate included not just the patient's concomitant illnesses, but also her social status and health insurance class and the sex of the gynecologist.

Sources: Deutsches Aerzteblatt International, AlphaGalileo Foundation.

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New Research Offers Pointers For Keeping To Your Exercise Resolutions

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Main Category: Sports Medicine / Fitness
Also Included In: Seniors / Aging;  Psychology / Psychiatry
Article Date: 17 Aug 2011 - 2:00 PDT window.fbAsyncInit = function() { FB.init({ appId: 'aa16a4bf93f23f07eb33109d5f1134d3', status: true, cookie: true, xfbml: true, channelUrl: 'http://www.medicalnewstoday.com/scripts/facebooklike.html'}); }; (function() { var e = document.createElement('script'); e.async = true; e.src = document.location.protocol + '//connect.facebook.net/en_US/all.js'; document.getElementById('fb-root').appendChild(e); }()); email icon email to a friend   printer icon printer friendly   write icon opinions  
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Sticking with an exercise routine means being able to overcome the obstacles that invariably arise. A key to success is having the confidence that you can do it, researchers report. A new study explores how some cognitive strategies and abilities increase this "situation-specific self-confidence," a quality the researchers call "self-efficacy."

"You can apply the concept of self-efficacy to every single health behavior you can think of because in many ways that really is what gets us through the day, gets us through the tough times," said University of Illinois kinesiology and community health professor Edward McAuley, who led the research. "People who are more efficacious tend to approach more challenging tasks, work harder and stick with it even in the face of early failures."

Those lacking self-efficacy often won't even try to start a new routine, or will quit at the earliest sign of difficulty, McAuley said. "Almost 50 percent of people who begin an exercise program drop out in the first six months," he said.

All is not lost, however, for those with low self-efficacy, McAuley said. Research has shown that there are ways to increase your confidence in relation to specific goals. Remembering previous successes, observing others doing something you find daunting and enlisting others' support can increase your self-efficacy enough to get you started. Every step toward your goal will further increase your confidence, he said.

In the new study, published in the American Journal of Preventive Medicine, McAuley and his colleagues were interested in whether specific cognitive abilities and strategies enhanced older adults' ability to stay with an exercise program by boosting their self-efficacy.

The researchers conducted a battery of cognitive tests on 177 men and women in their 60s and early 70s and also asked them whether and how often they set goals for themselves, monitored their progress, managed their time and engaged in other "self-regulatory" behaviors.

"These self-regulatory processes are really concerned with our ability to plan, to schedule physical activity into our daily life, to inhibit undesirable responses, such as sitting in front of the TV when you could be out working in your yard or walking around the block," McAuley said. "These processes can be measured in a very objective way."

The cognitive tests were "measures such as spatial memory, being able to multitask and being able to inhibit undesirable responses," he said. Collectively, these tests assess what is known as "executive function."

Participants were then randomly assigned either to a stretching, toning and balance program or a walking program that met three times a week for a year. Their self-efficacy was assessed after three weeks in the program.

The researchers found that some abilities and strategies did increase participants' adherence to the exercise programs. Two executive function skills - the ability to multitask and to inhibit undesirable responses - significantly contributed to adherence by increasing self-efficacy, the researchers found. And more frequent use of self-regulatory strategies such as goal-setting, time management, self-monitoring and recruiting others for support increased study subjects' participation in the program - again, by boosting their self-efficacy, McAuley said.

"We can potentially use this information to identify who might be poor adherers to an exercise program," McAuley said. "And then offer those people an array of different coping skills and strategies to inhibit or overcome bad behaviors."

Because executive function declines with age, McAuley said, previously sedentary older adults hoping to exercise more will likely benefit most if they adopt strategies that help them manage obstacles and build their self-efficacy.

Other studies have shown that aerobic exercise such as walking improves brain function in older adults. Thus, participation in an exercise program is likely to enhance cognitive functions that raise self-efficacy, positively reinforcing a person's ability to pursue his or her exercise goals, McAuley said.

Edward McAuley is also a part-time faculty member of the Beckman Institute for Advanced Science and Technology. Collaborators on this study from the Illinois department of kinesiology and community health include postdoctoral researcher Sean Mullen and students Amanda Szabo, Siobhan White, Thomas Wójcicki, Emily Mailey, Neha Gothe and Erin Olson. Collaborators from the Beckman Institute include graduate research assistant Michelle Voss, postdoctoral researcher Kirk Erickson (now at the University of Pittsburgh), former doctoral student Ruchika Prakash (now at Ohio State University) and Beckman Institute director Art Kramer, who is a professor of psychology.

The National Institute on Aging funded this research.

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Obese Mice Live Longer And Are Healthier When Given Synthetic Compound SRT1720

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Editor's Choice
Academic Journal
Main Category: Obesity / Weight Loss / Fitness
Also Included In: Diabetes;  Endocrinology;  Seniors / Aging
Article Date: 19 Aug 2011 - 16:00 PDT window.fbAsyncInit = function() { FB.init({ appId: 'aa16a4bf93f23f07eb33109d5f1134d3', status: true, cookie: true, xfbml: true, channelUrl: 'http://www.medicalnewstoday.com/scripts/facebooklike.html'}); }; (function() { var e = document.createElement('script'); e.async = true; e.src = document.location.protocol + '//connect.facebook.net/en_US/all.js'; document.getElementById('fb-root').appendChild(e); }()); email icon email to a friend   printer icon printer friendly   write icon opinions  
5 stars5 stars
Obese male mice who were given SRT1720, a synthetic compound, not only lived considerably longer, but also enjoyed healthier lives compared to other obese mice, researchers reported in the journal Scientific Reports. The obese mice that received the compound had improved function of the heart, pancreas and liver.

National Institute of Aging (NIA) Director Richard J. Hodes, M.D., said:

"This study has interesting implications for research on the biology of aging. It demonstrates that years of healthy life can be extended in an animal model of diet-induced obesity by a synthetic compound that modulates a gene pathway associated with aging."

The researchers commented that further studies are required to find out how pertinent these findings might be for human beings.

SRT1720 activates the SIRT1 enzyme, a type of sirtuin. Sirtuins are thought to be involved in the aging process and are believed to contribute to calorie restriction in higher organisms, including primates (non-human).

In this study, the researchers divided 1-year old (middle-aged) male mice into four groups: High dose of SRT1720, fed on a high-fat dietLow dose of dose of SRT1720, fed on a high-fat dietNo SRT1720, fed on a high-fat dietNo SRT1720, fed on a standard dietSenior author Rafael de Cabo, Ph.D., said:

"As we hypothesized, SRT1720 mimics dietary restriction, moderating many of the harmful effects of the high-fat diet and obesity. Furthermore, we found that the higher dose of the compound had a stronger effect and there were no signs of toxicity from SRT1720 even after 80 weeks of treatment."

The researchers' highlighted findings are listed below: The mice on high-dose SRT1720 lived 18% longer and those on a low-dose 4% longer than the obese mice on no SRT1720. From the age of 56 weeks onwards, the high-dose mice's mean lifespan was 44% longer and low-dose 11% longer than the no SRT1720 dose fat mice.The obese mice on SRT1720 had less fat build-up in their livers and superior liver function compared to the other obese mice. The SRT1720-treated mice had smaller livers than the obese mice not on SRT1720, but larger than the mice fed on a standard diet. SRT1720 was found to suppress liver inflammation, and prevent cell death in the liver.SRT1720 protected the obese mice from insulin resistance. Blood sugar measurements were about the same for all groups of mice, including the ones on a standard diet. The obese mice not on SRT1720 had insulin levels twice as high as the obese ones on SRT1720 and the other mice on a standard diet.HDL (High-density lipoprotein) levels were higher in the SRT1720 mice compared to those on the standard diet. HDL is known as good cholesterol. SRT1720 prevented cell death in the heart and suppressed inflammation.Oxygen consumption during periods of less activity was lower among the obese mice on SRT1720 compared to the other obese mice. The obese SRT1720 mice were more physically active than the obese mice not on SRT1720.Genes linked with aging in the liver were found to be suppressed by SRT172.Further tests demonstrated that SRT1720 had no effect on mice or cultures lacking the Sirt1 gene, it did, however, have an effect on mice and cultures with Sirt1. The authors wrote:

"In mice, SRT1720 reversed many of the health problems associated with a high-fat diet and did not have toxic side effects, but it is too early to know whether these findings could be replicated in other animal models, much less humans," said de Cabo. "The bottom line is that we need much more research before considering SRT1720 or related compounds as a possible treatment for diseases of aging."

Written by Christian Nordqvist
Copyright: Medical News Today
Not to be reproduced without permission of Medical News Today

Article Reference:
"SRT1720 improves survival and healthspan of obese mice"
Robin K. Minor, Joseph A. Baur, Ana P. Gomes, Theresa M. Ward, Anna Csiszar, Evi M. Mercken, Kotb Abdelmohsen, Yu-Kyong Shin, Carles Canto, Morten Scheibye-Knudsen, Melissa Krawczyk, Pablo M. Irusta, Alejandro Martín-Montalvo, Basil P. Hubbard, Yongqing Zhang, Elin Lehrmann, Alexa A. White, Nathan L. Price, William R. Swindell, Kevin J. Pearson et al.
Scientific Reports 1, Article number: 70 doi:10.1038/srep00070Bookmark and Share

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Public Bicycle Sharing Saves Lives And Protects Environment

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Editor's Choice
Academic Journal
Main Category: Public Health
Also Included In: Sports Medicine / Fitness;  Obesity / Weight Loss / Fitness
Article Date: 05 Aug 2011 - 0:00 PDT window.fbAsyncInit = function() { FB.init({ appId: 'aa16a4bf93f23f07eb33109d5f1134d3', status: true, cookie: true, xfbml: true, channelUrl: 'http://www.medicalnewstoday.com/scripts/facebooklike.html'}); }; (function() { var e = document.createElement('script'); e.async = true; e.src = document.location.protocol + '//connect.facebook.net/en_US/all.js'; document.getElementById('fb-root').appendChild(e); }()); email icon email to a friend   printer icon printer friendly   write icon opinions  
4 stars4 stars
A study published on bmj.com today reveals that public bicycle sharing schemes save lives and reduce greenhouse gas emissions. Although the aim of the increasingly popular public bicycle sharing schemes in cities worldwide is generally to ease traffic congestion, it also promotes health.

Dr David Rojas-Rueda and his researchers at the Center for Research in Environmental Epidemiology in Barcelona, Spain decided to study the health impact of the public bicycle sharing initiative in Barcelona called Bicing that was started in March 2007.

With 182,062 subscibers to Bicing by August 2009, representing 11% of Barcelona's municipal population, the average distance traveled by Bicing on a working day consisted of 3.29 km with an average of 14 minutes.

Researchers estimated the reduction in carbon dioxide emissions and number of fatal casualties linked to biking compared to driving for three main areas: physical activity, road traffic incident and exposure to air pollution. The study was based on a health impact model to integrate existing data from scientific studies and local travel information.

Calculations revealed an annual increase of 0.13 fatalities due to air pollution and 0.03 deaths through traffic accidents for cyclists compared with those driving a car, however, 12.46 deaths were avoided due to physical activity and therefore reducing the annual death toll for cyclists by a total 12.28. It was also estimated that the reduction in carbon emissions was reduced by over 9 million kg annually.

In a concluding statement the researchers said:

"Our work has shown that low cost public bicycle sharing systems aimed at encouraging commuters to cycle are worth implementing in other cities, not only for the health benefits but also for potential co-benefits such as a reduction in air pollution and greenhouse gasses."

Despite the necessity of further work, researchers added that the initial assessment is vital..:

"..to encourage cities to change car use by cycling and stimulate the implementation of bike sharing systems in cities to improve the health of the population."

Written by Petra Rattue
Copyright: Medical News Today
Not to be reproduced without permission of Medical News Today

Article Reference:
"The health risks and benefits of cycling in urban environments compared with car use: health impact assessment study"
David Rojas-Rueda, Audrey de Nazelle, Marko Tainio, Mark J Nieuwenhuijsen
BMJ 2011; 343:d4521Bookmark and Share

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